C-Jun Colorimetric Cell-Based ELISA Kit
The c-Jun Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor c-Jun protein expression profile in cells. The kit can be used for measuring the relative amounts of c-Jun in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on c-Jun.
Product Specifications
Synonyms
Activator protein 1; AH119; AP-1; AP1; c-Jun; Jun A; p39; Proto-oncogene c-jun; RJG-9; V-jun avian sarcoma virus 17 oncogene homolog
Gene Name
JUN
UniProt
P05412
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306) .
Molecular Weight
35676 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Transcription factor AP-1
Subcellular Location
Nucleus.
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