CD226 Colorimetric Cell-Based ELISA Kit
The CD226 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CD226 protein expression profile in cells. The kit can be used for measuring the relative amounts of CD226 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CD226.
Product Specifications
Synonyms
CD226; DNAM1; DNAX accessory molecule-1; PTA1; TLiSA1; adhesion glycoprotein; platelet and T cell activation antigen 1
Gene Name
CD226
UniProt
Q15762
Reactivity
Human, Mouse
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704) . Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T- cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705) .
Molecular Weight
38614 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
CD226 antigen
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
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