Catenin-gamma Colorimetric Cell-Based ELISA Kit
The Catenin-gamma Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Catenin-gamma protein expression profile in cells. The kit can be used for measuring the relative amounts of Catenin-gamma in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Catenin-gamma.
Product Specifications
Synonyms
CTNNG; DP3; Desmoplakin III; JUP; Junction plakoglobin; PDGB; PKGB; PLAK; catenin, gamma; gamma-catenin; plakoglobin
Gene Name
JUP
UniProt
P14923
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Common junctional plaque protein. The membrane- associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity) .
Molecular Weight
81745 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Junction plakoglobin
Subcellular Location
Cell junction, adherens junction.Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Cytoplasmic in a soluble and membrane-associated form.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MPX2279K Each
Magic™ Membrane Protein Human CLDN14 (Claudin 14) Expressed in vitro E.coli expression system, Full Length
Sign In for Pricing
View Details 
