Catenin-gamma Colorimetric Cell-Based ELISA Kit

The Catenin-gamma Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Catenin-gamma protein expression profile in cells. The kit can be used for measuring the relative amounts of Catenin-gamma in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Catenin-gamma.

Product Specifications

Synonyms

CTNNG; DP3; Desmoplakin III; JUP; Junction plakoglobin; PDGB; PKGB; PLAK; catenin, gamma; gamma-catenin; plakoglobin

Gene Name

JUP

UniProt

P14923

Reactivity

Human, Mouse, Rat

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Common junctional plaque protein. The membrane- associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity) .

Molecular Weight

81745 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1092

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1092

Other Gene Names

Junction plakoglobin

Subcellular Location

Cell junction, adherens junction.Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Cytoplasmic in a soluble and membrane-associated form.