CAMK2A/CAMK2D Colorimetric Cell-Based ELISA Kit
The CAMK2A/CAMK2D Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CAMK2A/CAMK2D protein expression profile in cells. The kit can be used for measuring the relative amounts of CAMK2A/CAMK2D in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CAMK2A/CAMK2D.
Product Specifications
Synonyms
CAMK2A; CaM-kinase II alpha chain; CaMK-II alpha subunit; CaMKII-alpha; Calcium/calmodulin-dependent protein kinase type II alpha chain; KCC2A; kinase CaMK2-alpha
Gene Name
CAMK2A
UniProt
Q9UQM7
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity) . Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378) . Activates FOXO3 transcriptional activity (By similarity) .
Molecular Weight
54088 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Calcium/calmodulin-dependent protein kinase type II subunit alpha
Subcellular Location
Cell junction, synapse, presynaptic cell membrane.Cell junction, synapse. Postsynaptic lipid rafts.
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