Calmodulin Colorimetric Cell-Based ELISA Kit
The Calmodulin Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Calmodulin protein expression profile in cells. The kit can be used for measuring the relative amounts of Calmodulin in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Calmodulin.
Product Specifications
Synonyms
CALM; CALM1; CALM2; CALM3; CAM; CAM1; CAM2; CAM3; CAMB; CAMC
Gene Name
CALM2 CAM2, CAMBCALM3 CALML2, CAM3, CAMC, CAMIIICALM1 CALM, CAM, CAM1
UniProt
P62158
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425) . Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752) . Positively regulates calcium-activated potassium channel activity of KCNN2 (PubMed:27165696) .
Molecular Weight
16838 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Calmodulin-2
Subcellular Location
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.
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