Kopsoffinol

Kopsoffinol, a bisindole alkaloid, shows in vitro growth inhibitory activity against human PC-3, HCT-116, MCF-7, and A549 cells and moderate effects in reversing multidrug-resistance in vincristine-resistant human KB cells[1].

Product Specifications

CAS Number

[96935-25-0]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kopsoffinol.html

Smiles

COC([C@H]1C[C@@]2(CCCN3CC4)[C@H]3[C@@]54C(C=C(C=C6)[C@@H]7N8C9=C(C%10=C8C=CC=C%10)CCN%11CCC[C@@](C7)([C@H](O)C)[C@@H]9%11)=C6N[C@]51CC2)=O

Molecular Formula

C40H48N4O3

Molecular Weight

632.83

References & Citations

[1]"Wai-Sum Yap, et al. Aspidofractinine and Eburnane Alkaloids from a North Borneo Kopsia. Ring-Contracted, Additional Ring-Fused, and Paucidactine-Type Aspidofractinine Alkaloids from K. pauciflora. J Nat Prod . 2016 Jan 22;79 (1) :230-9."