BAD Colorimetric Cell-Based ELISA Kit
The BAD Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BAD protein expression profile in cells. The kit can be used for measuring the relative amounts of BAD in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BAD.
Product Specifications
Synonyms
BAD; BBC6; Bcl- XL/Bcl-2 associated death promoter; Bcl-2 binding component 6; Bcl-2-like 8 protein; Bcl-xL/Bcl-2 associated death promoter; Bcl2-antagonist of cell death; BCL2L8
Gene Name
BAD
UniProt
Q92934
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed in a wide variety of tissues.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity) . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Molecular Weight
18392 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Bcl2-associated agonist of cell death
Subcellular Location
Mitochondrion outer membrane. Cytoplasm. Colocalizes with HIF3A in the cytoplasm (By similarity) . Upon phosphorylation, locates to the cytoplasm.
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