ATF7 Colorimetric Cell-Based ELISA Kit
The ATF7 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ATF7 protein expression profile in cells. The kit can be used for measuring the relative amounts of ATF7 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ATF7.
Product Specifications
Synonyms
ATFA; activating transcription factor 7, cyclic AMP-dependent transcription factor ATF-7
Gene Name
ATF7
UniProt
P17544
Reactivity
Human, Mouse
Tissue Specificity
Expressed in heart, lung and skeletal muscle. Isoform 4 is expressed in various tissues including heart, brain, placenta, lung and skeletal muscle. Highest levels in skeletal muscle. Lowest in lung and placenta.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]- 3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
Molecular Weight
52967 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Cyclic AMP-dependent transcription factor ATF-7
Subcellular Location
Nucleus. Nucleus, nucleoplasm. Mainly nucleoplasmic. Restricted distribution to the perinuculear region. The sumoylated form locates to the nuclear periphery.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1170803-01 0.02 mg (E-Coli)
Recombinant Rabbit Protein S100-A12 (S100A12)
Sign In for Pricing
View Details MBS1170803-02 0.1 mg (E-Coli)
Recombinant Rabbit Protein S100-A12 (S100A12)
Sign In for Pricing
View Details MBS1170803-03 0.02 mg (Yeast)
Recombinant Rabbit Protein S100-A12 (S100A12)
Sign In for Pricing
View Details MBS1170803-04 0.1 mg (Yeast)
Recombinant Rabbit Protein S100-A12 (S100A12)
Sign In for Pricing
View Details