ATF1 Colorimetric Cell-Based ELISA Kit
The ATF1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ATF1 protein expression profile in cells. The kit can be used for measuring the relative amounts of ATF1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ATF1.
Product Specifications
Synonyms
ATF1; Activating transcription factor 1; Cyclic-AMP-dependent transcription factor ATF-1; TCR-ATF1; TREB36 protein
Gene Name
ATF1
UniProt
P18846
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Molecular Weight
29233 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Cyclic AMP-dependent transcription factor ATF-1
Subcellular Location
Nucleus.
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