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AOS1 Colorimetric Cell-Based ELISA Kit

The AOS1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor AOS1 protein expression profile in cells. The kit can be used for measuring the relative amounts of AOS1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on AOS1.

Product Specifications

Synonyms

SUMO-activating enzyme subunit 1; Ubiquitin-like 1-activating enzyme E1A; SAE1; AOS1; SUA1; UBLE1A

Gene Name

SAE1

UniProt

Q9UBE0

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expression level increases during S phase and drops in G2 phase (at protein level) .

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Molecular Weight

38450 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1031

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1031

Other Gene Names

SUMO-activating enzyme subunit 1

Subcellular Location

Nucleus.

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