OCT2 Colorimetric Cell-Based ELISA Kit
The OCT2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor OCT2 protein expression profile in cells. The kit can be used for measuring the relative amounts of OCT2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on OCT2.
Product Specifications
Synonyms
POU domain class 2 transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2; POU2F2; OCT2; OTF2
Gene Name
POU2F2
UniProt
P09086
Reactivity
Human, Mouse
Tissue Specificity
Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') . Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.
Molecular Weight
51209 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
POU domain, class 2, transcription factor 2
Subcellular Location
Cytoplasm. Nucleus.
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