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Anti-Phospho Tensin-2 (Tyr483) Antibody

Boster Bio Anti-Phospho Tensin-2 (Tyr483) Antibody (Catalog# P30917) . Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2

Gene Name

TNS2

UniProt

Q63HR2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A phospho-peptide derived from human Tensin-2 around the phosphorylation site of Tyr483.

Clonality

Polyclonal

Tissue Specificity

Detected in heart, kidney, brain, thymus, spleen, liver, placenta, lung, skeletal muscle and small intestine.

Applications

WB, ELISA

Field of Research

Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling.

Molecular Weight

152580 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Tensin-2

Subcellular Location

Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Detected at the end of actin stress fibers. Detected in cytoplasmic punctate bodies (PubMed:22019427) .

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