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Anti-Phospho MKP-1/2 (Ser296/318) DUSP1 Antibody

Boster Bio Anti-Phospho MKP-1/2 (Ser296/318) DUSP1 Antibody (Catalog# P30451) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

DUSP1; CL100; MKP1; PTPN10; VH1; Dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; Mitogen-activated protein kinase phosphatase 1; MAP kinase phosphatase 1; MKP-1; Protein-tyrosine phosphatase CL100; DUSP4

Gene Name

DUSP1

UniProt

P28562

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human MKP-1/2 around the phosphorylation site of Ser296/318. Immunogen sequence location: 261-310

Clonality

Polyclonal

Tissue Specificity

Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Protein Phosphorylation, Ser/Thr Phosphatases, Signal Transduction, Tyrosine Phosphatases

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.

Molecular Weight

39298 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=P30451

Product MSDS

https://www.bosterbio.com/msds?sku=P30451

Fragment

Rabbit IgG

Other Gene Names

Dual specificity protein phosphatase 1

Subcellular Location

Nucleus.

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