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Anti-Phospho GRF-1 (Tyr1105) Antibody

Boster Bio Anti-Phospho GRF-1 (Tyr1105) Antibody (Catalog# P30433) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

ARHGAP35; GRF1; GRLF1; KIAA1722; Rho GTPase-activating protein 35; Glucocorticoid receptor DNA-binding factor 1; Glucocorticoid receptor repression factor 1; GRF-1; Rho GAP p190A; p190-A

Gene Name

ARHGAP35

UniProt

Q9NRY4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human GRF-1 around the phosphorylation site of Tyr1105.

Clonality

Polyclonal

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Co-Factors, Epigenetics and Nuclear Signaling, Transcription

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Sensitivity

<10pg/ml

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'- GAGAAAAGAAACTGGAGAAACTC-3' (PubMed:1894621) . May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP) (By similarity) . Modulates Rho GTPase-dependent F-actin polymerization and is involved in the positive regulation of ciliogenesis and cilia elongation (By similarity) .

Molecular Weight

170514 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Rho GTPase-activating protein 35

Subcellular Location

Cytoplasm. Nucleus.Cytoplasm, cytoskeleton, cilium basal body.

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