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Anti-Acetylated Histone H1 (Lys25) H1FOO Antibody

Boster Bio Anti-Acetylated Histone H1 (Lys25) H1FOO Antibody (Catalog# P12111) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Monkey.

Product Specifications

Synonyms

H1FOO; H1OO; OSH1; Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1; H1K25AC

Gene Name

H1FOO

UniProt

Q8IZA3

Host

Rabbit

Reactivity

Human, Monkey

Immunogen

A peptide derived from human Histone H1 around the acetylated site of Lys25. Immunogen sequence location: 131 - 180

Clonality

Polyclonal

Tissue Specificity

Oocyte-specific.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling, Histones, Unmodified

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using acetylated peptide. The antibody against non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity) .

Molecular Weight

35813 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Histone H1oo

Subcellular Location

Cytoplasm. Nucleus. Chromosome.

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