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Anti-Phospho-Dok-2 (Y299) Antibody

Boster Bio Anti-Phospho-Dok-2 (Y299) Antibody catalog # P07956-1. Tested in WB applications. This antibody reacts with Human, Monkey, Mouse.

Product Specifications

Synonyms

Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2) ; DOK2

Gene Name

DOK2

UniProt

O60496

Host

Rabbit

Reactivity

Human, Mouse, Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr299. AA range:266-315

Tissue Specificity

Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver. .

Applications

WB

Purification

Immunogen affinity purified

Dilution

WB, 1:500-1:2000

Form

Liquid

Function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity) . .

Molecular Weight

45379 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Docking protein 2

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