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Anti-Phospho TIF-IA (Ser649) Antibody

Boster Bio Anti-Phospho TIF-IA (Ser649) Antibody (Catalog# P05439) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

RRN3; TIFIA; RNA polymerase I-specific transcription initiation factor RRN3; Transcription initiation factor IA; TIF-IA

Gene Name

RRN3

UniProt

Q9NYV6

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human TIF-IA around the phosphorylation site of Ser649. Immunogen sequence location: 602-651

Clonality

Polyclonal

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Epigenetics and Nuclear Signaling, Polymerase Associated Factors, Transcription

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC) . Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction (By similarity) .

Molecular Weight

74107 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

RNA polymerase I-specific transcription initiation factor RRN3

Subcellular Location

Nucleus, nucleolus.

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