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Anti-Phospho-Ksr-1 (Ser392) Antibody

Boster Bio Anti-Phospho-Ksr-1 (Ser392) Antibody (Catalog # P03285) . Tested in WB, IHC, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Kinase suppressor of Ras 1; KSR1; KSR

Gene Name

KSR1

UniProt

Q8IVT5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human Ksr-1 around the phosphorylation site of S392.

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Field of Research

MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Tyrosine Kinases

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself. .

Molecular Weight

102160 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Kinase suppressor of Ras 1

Subcellular Location

Cytoplasm . Membrane ; Peripheral membrane protein . Cell membrane ; Peripheral membrane protein . Cell projection, ruffle membrane . Endoplasmic reticulum membrane . In unstimulated cells, where the phosphorylated form is bound to a 14-3-3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery. .

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