What is the catalog number for Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody?

The catalog number for Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody is P01992.

What sizes are available for Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody?

Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody in stock?

Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody?

The safety data sheet for Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody is available here: https://www.bosterbio.com/msds?sku=P01992.

Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody

Boster Bio Anti-Phospho-PERK (T981) Rabbit Polyclonal Antibody catalog # P01992. Tested in ELISA, IF, IHC-P, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Eukaryotic translation initiation factor 2-alpha kinase 3;2.7.11.1; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK; EIF2AK3; PEK, PERK

Gene Name

EIF2AK3

UniProt

Q9NZJ5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PEK/PERK around the phosphorylation site of Thr981. AA range:947-996

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. A high level expression is seen in secretory tissues.

Applications

ELISA, IF, IHC-P, WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity_x0002_chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR) -induced G1 growth arrest due to the loss of cyclin-D1 (CCND1) . Involved in control of mitochondrial morphology and function (By similarity) . .