Anti-Phospho-FADD (S194) Antibody
Boster Bio Anti-Phospho-FADD (S194) Antibody catalog # P00237. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADD; FADD; MORT1; GIG3
Gene Name
FADD
UniProt
Q13158
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human FADD around the phosphorylation site of Ser194. AA range:159-208
Clonality
Polyclonal
Tissue Specificity
Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
Applications
ELISA, IHC-P, WB
Purification
Immunogen affinity purified
Concentration
1 mg/ml
Form
Liquid
Function
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. .
Molecular Weight
23279 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
FAS-associated death domain protein
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