BACE1, Human (HEK293, Fc)
BACE1 protein is crucial in proteolytic processing of amyloid precursor protein (APP), initiating cleavage at the N-terminus of the A-beta peptide sequence.This process results in the extracellular release of beta-cleaved soluble APP and a cell-associated C-terminal fragment.BACE1's cleavage activity extends to CHL1, demonstrating its versatility in substrate processing.BACE1 Protein, Human (HEK293, Fc) is the recombinant human-derived BACE1 protein, expressed by HEK293 , with C-hFc labeled tag.
Product Specifications
Product Name Alternative
BACE1 Protein, Human (HEK293, Fc), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/bace-1-protein-human-436a-a-hek293-fc.html
Molecular Formula
23621 (Gene_ID) P56817-1 (T22-T457) (Accession)
Molecular Weight
Approximately 100-105 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
Frequently Asked Questions
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