Anti-Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Monoclonal Antibody

Boster Bio Anti-Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Monoclonal Antibody (Catalog # M12092-1) . Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Monkey, Cow, Dog, Rabbit, Mouse, Rat, Chicken.

Product Specifications

Background

This monoclonal antibody recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1) ; 64kDa (CK3) ; 59kDa (CK4) ; 58kDa (CK5) ; 56kDa (CK6) ; 52kDa (CK8) . Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. This monoclonal antibody recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

Synonyms

Keratin, type II cytoskeletal 2 oral; Cytokeratin-2P; CK-2P; K2P; Keratin-76; K76; Type-II keratin Kb9; KRT76; KRT2B, KRT2P

Gene Name

KRT76

UniProt

Q01546

Host

Mouse

Reactivity

Human, Monkey, Cow, Dog, Rabbit, Mouse, Rat, Chicken

Immunogen

Human epidermal keratin

Clonality

Monoclonal

Clone

Clone: Clone: SPM116

Applications

Flow Cytometry, IF, WB, IHC

Field of Research

Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Signal Transduction, Subcellular Markers, Tags & Cell Markers

Purification

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Function

Probably contributes to terminal cornification. .

Molecular Weight

65841 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.