Anti-IL-17RE Antibody (Monoclonal, ABM2G70)

Boster Bio Anti-IL-17RE Antibody (Monoclonal, ABM2G70) (Catalog# M11492) . Tested in FACS, WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Interleukin-17 receptor E; IL-17 receptor E; IL-17RE; IL17RE; UNQ3056/PRO9877

Gene Name

IL17RE

UniProt

Q8NFR9

Host

Mouse

Reactivity

Human, Mouse

Immunogen

A partial length recombinant human IL-17RE protein (amino acids 50-268)

Clonality

Monoclonal

Clone

Clone: ABM2G70

Tissue Specificity

Predominantly expressed in mucosal tissues with high levels in keratinocytes and colon epithelial cells. Very low expression in dermal fibroblasts. Expressed in various tumor cell lines.

Applications

FACS, WB

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

Protein G Chromatography

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Specific functional receptor for IL17C. May be signaling through the NF-κ-B and MAPK pathways. May require TRAF3IP2 /ACT1 for signaling. May be a crucial regulator in innate immunity to bacterial pathogens. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors. .