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Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1)

Boster Bio Anti-PIDD PIDD1 Antibody (Monoclonal, Anto-1) (Catalog# M10708) . Tested in IHC-P, WB application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

P53-induced death domain-containing protein 1; Leucine-rich repeat and death domain-containing protein; PIDD1; LRDD, PIDD

Gene Name

PIDD1

UniProt

Q9HB75

Host

Mouse

Reactivity

Human, Mouse

Immunogen

Recombinant human PIDD death domain (aa 776-910)

Clonality

Monoclonal

Clone

Clone: Anto-1

Tissue Specificity

Ubiquitous.

Applications

IHC-P, WB

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. Associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. Associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which an important regulator in apoptotic pathways. .

Molecular Weight

99712 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for long-term storage. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20° C.

Fragment

IgG1

Other Gene Names

P53-induced death domain-containing protein 1

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

P53-induced death domain-containing protein 1 (PIDD1)

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