Anti-IL-36R IL1RL2 Antibody (Monoclonal, ABM47A2)

Boster Bio Anti-IL-36R IL1RL2 Antibody (Monoclonal, ABM47A2) (Catalog# M09203) . Tested in FACS, WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Interleukin-1 receptor-like 2; IL-36 receptor; IL-36R; Interleukin-1 receptor-related protein 2; IL-1Rrp2; IL1R-rp2; IL1RL2; IL1RRP2

Gene Name

IL1RL2

UniProt

Q9HB29

Host

Mouse

Reactivity

Human

Immunogen

A partial length recombinant IL-36R protein (amino acids 1-203)

Clonality

Monoclonal

Clone

Clone: ABM47A2

Tissue Specificity

Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte- derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level.

Applications

FACS, WB

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

Protein G Chromatography

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Receptor for interleukin-36 (IL36A, IL36B and IL36G) . After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity) . The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL- 23/IL-17/IL-22 pathway. .