Anti-APIP Antibody (Monoclonal, ABM19C7)

Boster Bio Anti-APIP Antibody (Monoclonal, ABM19C7) (Catalog# M09029) . Tested in WB, FACS application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Methylthioribulose-1-phosphate dehydratase; MTRu-1-P dehydratase;4.2.1.109; APAF1-interacting protein; hAPIP; APIP; CGI-29

Gene Name

APIP

UniProt

Q96GX9

Host

Mouse

Reactivity

Human

Immunogen

Full length recombinant protein of APIP

Clonality

Monoclonal

Clone

Clone: ABM19C7

Tissue Specificity

Isoform 1 is ubiquitously expressed. Isoform 2 is expressed at lower levels and detected in heart, brain, pancreas, liver, placenta, skeletal muscle and kidney.

Applications

WB, FACS

Field of Research

Apoptosis, Associated Proteins, Cell Biology, Intracellular

Purification

Protein G Chromatography

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) . Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death. .