Anti-Histone H2B Rabbit Monoclonal Antibody, Clone#RM230

Boster Bio Anti-Histone H2B Rabbit Monoclonal Antibody, Clone#RM230 (Catalog # M08989) . Tested in WB, ICC. ELISA, Luminex applications. This antibody reacts with Vertebrates.

Product Specifications

Synonyms

Histone H2B type 1-J; Histone H2B.1; Histone H2B.r; H2B/r; HIST1H2BJ; H2BFR

Gene Name

HIST1H2BJ

UniProt

P06899

Host

Rabbit

Reactivity

Vertebrates

Cross Reactivity

This antibody reacts to the Histone H2B protein, independent of post-translational modifications. No cross-reactivity with other histone proteins.

Immunogen

A peptide corresponding to the C-terminus of human Histone H2B.

Clonality

Monoclonal

Clone

Clone: RM230

Applications

WB, ICC, ELISA, Luminex

Field of Research

Epigenetics and Nuclear Signaling, Histones, Unmodified

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

1 mg/mL

Form

Liquid

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.