Anti-Histone H3 (Unmodified Lys4) Rabbit Monoclonal Antibody, Clone#RM186
Boster Bio Anti-Histone H3 (Unmodified Lys4) Rabbit Monoclonal Antibody, Clone#RM186 (Catalog # M08865) . Tested in WB, ELISA, Luminex, ICC applications. This antibody reacts with Human, Vertebrates.
Product Specifications
Synonyms
Histone H3.1t; H3/t; H3t; H3/g; HIST3H3; H3FT
Gene Name
HIST3H3
UniProt
Q16695
Host
Rabbit
Reactivity
Human, Vertebrates
Cross Reactivity
This antibody recognizes Histone H3 that is unmodified at Lys4 but does not recognize acetylated or methylated Lys4. The antibody binding specificity allows for modifications of Arg2, Thr3, and/or other modifications in Histone H3.
Immunogen
An unmodified peptide corresponding to the N-terminus of Histone H3.
Clonality
Monoclonal
Clone
Clone: RM186
Tissue Specificity
Expressed in testicular cells.
Applications
WB, ELISA, Luminex, ICC
Field of Research
2339, Epigenetics and Nuclear Signaling, Histones
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Concentration
1 mg/mL
Form
Liquid
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Molecular Weight
15508 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Fragment
Rabbit IgG
Other Gene Names
Histone H3.1t
Subcellular Location
Nucleus. Chromosome.
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