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Anti-Keratin KRT6C Monoclonal Antibody

Boster Bio Anti-Keratin KRT6C Monoclonal Antibody (Catalog # M07078) . Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Background

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. There are two types of keratins (cytoskeletal and microfibrillar) and are clustered in a region of chromosome. Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e. skin) and non-keratinizing cells (i.e. mesothelial) . Anti-Keratin Antibody is useful for researchers interested in cytoskeletal signaling and developmental biology research.

Synonyms

Keratin, cytokeratin 6, PC2, Type II keratin isoform K6c

Gene Name

KRT6C

UniProt

P48668

Host

Mouse

Reactivity

Human

Immunogen

This protein A purified monoclonal antibody was produced by repeated immunizations with purified human cytoskeletal preparations from A431 cells.

Clonality

Monoclonal

Clone

Clone: Clone: C11

Tissue Specificity

Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.

Applications

ELISA, IF, IHC, WB

Field of Research

Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Keratin, Signal Transduction

Purification

This protein A purified mouse monoclonal antibody reacts specifically with keratins from human tissues and derived cell lines. This antibody reacts with keratin (56 kDa), keratin 17 (46 kDa), keratin 18 (45 kDa) and keratin 19 (40 kDa) derived from humans. Cross-reactivity with keratins from other sources has not been determined. No reaction is expected against other filament proteins including vimentin, desmin and neurofilament protein.

Concentration

1.3 mg/mL by UV absorbance at 280 nm

Form

Liquid (sterile filtered)

Molecular Weight

60025 MW

Shipping Conditions

Due to dry ice shipping issues, this product is temporarily not available to distributors outside of the United States.

Storage Conditions

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

Fragment

IgG1

Applications Notes

Anti-Keratin Antibody has been tested in ELISA, immunohistochemistry, immunofluorescence, immunoblotting and immunoprecipitation. For a positive control use skin, colon carcinoma and squamous granulocyte carcinoma cells.

Other Gene Names

Keratin, type II cytoskeletal 6C

Frequently Asked Questions

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