Anti-GP2 (Glycoprotein 2) / ZAP75 Monoclonal Antibody

Boster Bio Anti-GP2 (Glycoprotein 2) / ZAP75 Monoclonal Antibody (Catalog # M06630) . Tested in ELISA, WB, IHC applications. This antibody reacts with Human.

Product Specifications

Background

GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD) . GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.

Synonyms

Pancreatic secretory granule membrane major glycoprotein GP2; Pancreatic zymogen granule membrane protein GP-2; ZAP75; GP2

Gene Name

GP2

UniProt

P55259

Host

Mouse

Reactivity

Human

Immunogen

Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)

Clonality

Monoclonal

Clone

Clone: Clone: GP2/1712

Tissue Specificity

Pancreatic secretory (zymogen) granule.

Applications

ELISA, WB, IHC

Field of Research

Microbiology, Protein

Purification

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Molecular Weight

59480 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.