What is the catalog number for Anti-Splicing Factor SF3B4 Monoclonal Antibody?

The catalog number for Anti-Splicing Factor SF3B4 Monoclonal Antibody is M06414.

Is Anti-Splicing Factor SF3B4 Monoclonal Antibody in stock?

Anti-Splicing Factor SF3B4 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Splicing Factor SF3B4 Monoclonal Antibody?

The safety data sheet for Anti-Splicing Factor SF3B4 Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M06414.

Anti-Splicing Factor SF3B4 Monoclonal Antibody

Boster Bio Anti-Splicing Factor SF3B4 Monoclonal Antibody catalog # M06414. Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Splicing factor 3B subunit 4; Pre-mRNA-splicing factor SF3b 49 kDa subunit; Spliceosome-associated protein 49; SAP 49; SF3B4; SAP49

Gene Name

SF3B4

UniProt

Q15427

Host

Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Full length recombinant human SF3B4 expressed in and purified from E. coli

Clonality

Monoclonal

Applications

IF, IHC, WB

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing, Splicing

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

WB: 1:1,000. IF/ICC and IHC: 1:1,000

Function

Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643) . SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937) . May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well (PubMed:10882114) . Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077) . .