Anti-Napsin A (Lung Adenocarcinoma Marker) NAPSA Monoclonal Antibody

Boster Bio Anti-Napsin A (Lung Adenocarcinoma Marker) NAPSA Monoclonal Antibody (Catalog # M05685-1) . Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human.

Product Specifications

Background

Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Synonyms

Napsin-A;3.4.23.-; Aspartyl protease 4; ASP4; Asp 4; Napsin-1; TA01/TA02; NAPSA; NAP1, NAPA

Gene Name

NAPSA

UniProt

O96009

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)

Clonality

Monoclonal

Clone

Clone: Clone: NAPSA/1238 + NAPSA/1239

Tissue Specificity

Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes.

Applications

Flow Cytometry, IF, WB, IHC

Field of Research

Cell Biology, Cell Type Markers, Proteolysis/Ubiquitin, Proteolytic Enzymes, Tags & Cell Markers, Tumor Associated

Purification

200ug/ml of antibody purified from rabbit anti-serum by Protein A.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Function

May be involved in processing of pneumocyte surfactant precursors.

Molecular Weight

45387 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.