Anti-Spectrin beta III (SPTBN2) Monoclonal Antibody

Boster Bio Anti-Spectrin beta III (SPTBN2) Monoclonal Antibody (Catalog # M05492) . Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Background

Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.

Synonyms

Spectrin beta chain, non-erythrocytic 2; Beta-III spectrin; Spinocerebellar ataxia 5 protein; SPTBN2; KIAA0302, SCA5

Gene Name

SPTBN2

UniProt

O15020

Host

Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary)

Clonality

Monoclonal

Clone

Clone: Clone: SPTBN2/1584

Tissue Specificity

Highly expressed in brain, kidney, pancreas, and liver, and at lower levels in lung and placenta.

Applications

Flow Cytometry, IF, WB, IHC

Field of Research

Actin Binding Proteins, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Neurodegenerative Disease, Neurology Process, Neuroscience, Signal Transduction

Purification

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Function

Probably plays an important role in neuronal membrane skeleton.

Molecular Weight

271325 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.