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Anti-Adenylate Cyclase III Antibody

Boster Bio Anti-Adenylate Cyclase III Antibody catalog # M04795. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Adenylate cyclase type 3;4.6.1.1; ATP pyrophosphate-lyase 3; Adenylate cyclase type III; AC-III; Adenylate cyclase, olfactive type; Adenylyl cyclase 3 ; AC3 ; ADCY3; KIAA0511

Gene Name

ADCY3

UniProt

O60266

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

C-terminal peptide of rat ACIII, PAAFPNGSSVTLPHQVVDNP with a Cys added to the N-terminus to allow coupling to KLH.

Clonality

Polyclonal

Tissue Specificity

Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699) . Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle (PubMed:9920776) . Detected in testis (PubMed:15705663) . .

Applications

IHC, WB, IF, ICC

Field of Research

Cancer, Cancer Metabolism, Energy Transfer Pathways, G Protein Signaling, Integration Of Energy, Integration Of Energy Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Signaling Pathway

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

WB: 1:1,000. IF/ICC or IHC: 1:10,000-20,000.

Function

Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet. .

Molecular Weight

128960 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M04795

Product MSDS

https://www.bosterbio.com/msds?sku=M04795

Other Gene Names

Adenylate cyclase type 3

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cell projection, cilium . Golgi apparatus . Also detected in the cytoplasm, close to lipid droplets. .
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