Anti-Adenylate Cyclase III Antibody
Boster Bio Anti-Adenylate Cyclase III Antibody catalog # M04795. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Adenylate cyclase type 3;4.6.1.1; ATP pyrophosphate-lyase 3; Adenylate cyclase type III; AC-III; Adenylate cyclase, olfactive type; Adenylyl cyclase 3 ; AC3 ; ADCY3; KIAA0511
Gene Name
ADCY3
UniProt
O60266
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
C-terminal peptide of rat ACIII, PAAFPNGSSVTLPHQVVDNP with a Cys added to the N-terminus to allow coupling to KLH.
Clonality
Polyclonal
Tissue Specificity
Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699) . Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle (PubMed:9920776) . Detected in testis (PubMed:15705663) . .
Applications
IHC, WB, IF, ICC
Field of Research
Cancer, Cancer Metabolism, Energy Transfer Pathways, G Protein Signaling, Integration Of Energy, Integration Of Energy Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Signaling Pathway
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Dilution
WB: 1:1,000. IF/ICC or IHC: 1:10,000-20,000.
Function
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet. .
Molecular Weight
128960 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Adenylate cyclase type 3
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cell projection, cilium . Golgi apparatus . Also detected in the cytoplasm, close to lipid droplets. .
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