Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378

Boster Bio Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 (Catalog # M04431-1) . Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

POU domain class 2-associating factor 1; B-cell-specific coactivator OBF-1; BOB-1; OCA-B; OCT-binding factor 1; POU2AF1; OBF1

Gene Name

POU2AF1

UniProt

Q16633

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody reacts to human BOB-1/OBF-1 (B-cell-specific coactivator) (POU domain class 2-associating factor 1)

Immunogen

A peptide corresponding to the C-terminus of human BOB-1/OBF-1

Clonality

Monoclonal

Clone

Clone: RM378

Tissue Specificity

B-cell specific.

Applications

IHC, WB

Field of Research

Adaptive Immunity, B Cells, Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Immunology, Non-CD, Transcription

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.