Anti-CD10 MME Rabbit Monoclonal Antibody, Clone#RM337

Boster Bio Anti-CD10 MME Rabbit Monoclonal Antibody, Clone#RM337 (Catalog # M04065-2) . Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Neprilysin;3.4.24.11 ; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10; MME; EPN

Gene Name

MME

UniProt

P08473

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody reacts to the cytoplasmic domain of human CD10.

Immunogen

A peptide corresponding to the N-terminus of human CD10.

Clonality

Monoclonal

Clone

Clone: RM337

Applications

IHC, WB

Field of Research

Angiogenesis, Atherosclerosis, Cancer, Cardiovascular, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction, Tumor Biomarkers

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535) . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991) . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675) . Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573) .