Anti-CD10 MME Rabbit Monoclonal Antibody, Clone#RM337
Selected Variant
M04065-2
Size: 100 µL
Boster Bio Anti-CD10 MME Rabbit Monoclonal Antibody, Clone#RM337 (Catalog # M04065-2) . Tested in IHC, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Neprilysin;3.4.24.11 ; Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase; SFE; CD10; MME; EPN
Gene Name
MME
UniProt
P08473
Host
Rabbit
Reactivity
Human
Cross Reactivity
This antibody reacts to the cytoplasmic domain of human CD10.
Immunogen
A peptide corresponding to the N-terminus of human CD10.
Clonality
Monoclonal
Clone
Clone: RM337
Applications
IHC, WB
Field of Research
Angiogenesis, Atherosclerosis, Cancer, Cardiovascular, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction, Tumor Biomarkers
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form
Liquid
Function
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535) . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991) . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675) . Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276) . Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573) .
Molecular Weight
85514 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Fragment
Rabbit IgG
Other Gene Names
Neprilysin
Subcellular Location
Cell membrane; Single-pass type II membrane protein.
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