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Anti- Alpha-internexin INA NF66 Antibody

Boster Bio Anti- Alpha-internexin INA NF66 Antibody catalog # M03756-2. Tested in IF, IHC, WB applications. This antibody reacts with Bovine, Equine, Human, Mouse, Pig, Rat.

Product Specifications

Synonyms

Integrin alpha ina-1; ina-1; F54G8.3

Gene Name

Ina-1

UniProt

Q03600

Host

Rabbit

Reactivity

Human, Rat, Mouse, Bovine, Pig, Equine

Immunogen

Purified recombinant rat -internexin expressed in and purified from E. coli.

Clonality

Polyclonal

Applications

IF, IHC, WB

Sensitivity

>5000 cells

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

Western blot: 1:10,000-1:20,000. ICC/IF and IHC: 1:500-1:1,000.

Function

Plays a role in cell migration, axon fasciculation, and morphogenesis (PubMed:9247263) . During gonad morphogenesis, involved in distal tip cells (DTC) -mediated guidance of gonad elongation, in maintaining their sharp tapering morphology and in their migration (PubMed:19023419, PubMed:22732572) . Involved in the anterior-posterior positioning of QR neuroblast descendants by regulating the migratory speed of QR.p (PubMed:25373777) . Probably by acting as a receptor for apoptotic cells, plays a role in the clearance of apoptotic cells during mid-embryogenesis (PubMed:20226672) . .

Molecular Weight

127767 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M03756-2

Product MSDS

https://www.bosterbio.com/msds?sku=M03756-2

Other Gene Names

Integrin alpha ina-1

Subcellular Location

Membrane ; Single-pass type I membrane protein . Cell projection, phagocytic cup . Cytoplasmic vesicle, phagosome membrane . Enriched at the cell contact with apoptotic cells and in phagocytic pseudopods during apoptotic cell engulfment. Co-localizes with src-1 during phagosome cup formation. .
Curated Selection

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