Anti- Alpha-internexin/NF66 Monoclonal Antibody
Boster Bio Anti- Alpha-internexin/NF66 Monoclonal Antibody catalog # M03756-1. Tested in IF, IHC, WB applications. This antibody reacts with Bovine, Human, Mouse, Rat.
Product Specifications
Synonyms
Integrin alpha ina-1; ina-1; F54G8.3
Gene Name
Ina-1
UniProt
Q03600
Host
Mouse
Reactivity
Human, Rat, Mouse, Bovine
Immunogen
E. coli.
Clonality
Monoclonal
Applications
IF, IHC, WB
Sensitivity
>5000 cells
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Dilution
WB: 1:10,000. IF/ICC and IHC: 1:5,000.
Function
Plays a role in cell migration, axon fasciculation, and morphogenesis (PubMed:9247263) . During gonad morphogenesis, involved in distal tip cells (DTC) -mediated guidance of gonad elongation, in maintaining their sharp tapering morphology and in their migration (PubMed:19023419, PubMed:22732572) . Involved in the anterior-posterior positioning of QR neuroblast descendants by regulating the migratory speed of QR.p (PubMed:25373777) . Probably by acting as a receptor for apoptotic cells, plays a role in the clearance of apoptotic cells during mid-embryogenesis (PubMed:20226672) . .
Molecular Weight
127767 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Integrin alpha ina-1
Subcellular Location
Membrane ; Single-pass type I membrane protein . Cell projection, phagocytic cup . Cytoplasmic vesicle, phagosome membrane . Enriched at the cell contact with apoptotic cells and in phagocytic pseudopods during apoptotic cell engulfment. Co-localizes with src-1 during phagosome cup formation. .
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