Anti-CD50 / ICAM-3 Monoclonal Antibody

Boster Bio Anti-CD50 / ICAM-3 Monoclonal Antibody (Catalog # M03651-1) . Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human.

Product Specifications

Background

Recognizes an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This monoclonal antibody is excellent for staining of formalin/paraffin tissues.

Synonyms

Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD50; ICAM3

Gene Name

ICAM3

UniProt

P32942

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human ICAM3 protein

Clonality

Monoclonal

Clone

Clone: Clone: ICAM3/1019

Applications

Flow Cytometry, IF, WB, IHC

Field of Research

Adapters, Cell Type Markers, Immunology, Protein Phosphorylation, Signal Transduction, Transmembrane

Purification

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

Concentration

Purified antibody with BSA and azide at 200ug/ml

Form

Liquid

Function

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) . ICAM3 is also a ligand for integrin alpha-D/beta-2.

Molecular Weight

59541 MW

Shipping Conditions

Available

Storage Conditions

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.