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Anti-Matrix metalloproteinase-12 (MMP-12) Rabbit Monoclonal Antibody, Clone#RM381

Boster Bio Anti-Matrix metalloproteinase-12 (MMP-12) Rabbit Monoclonal Antibody, Clone#RM381 (Catalog # M01520-1) . Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Macrophage metalloelastase; MME;3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12; MMP12; HME

Gene Name

MMP12

UniProt

P39900

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody reacts to human Matrix metalloproteinase-12 (MMP-12)

Immunogen

A peptide corresponding to C-terminus of human Matrix metalloproteinase-12 (MMP-12)

Clonality

Monoclonal

Clone

Clone: RM381

Tissue Specificity

Found in alveolar macrophages but not in peripheral blood monocytes.

Applications

IHC, WB

Field of Research

Angiogenesis, Atherosclerosis, Cancer, Cardiovascular, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction, Tumor Biomarkers

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

Molecular Weight

54002 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Macrophage metalloelastase

Subcellular Location

Secreted, extracellular space, extracellular matrix.

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