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Anti-CK-14 (Cytokeratin-14) KRT14 Rabbit Monoclonal Antibody, Clone#RM328

Boster Bio Anti-CK-14 (Cytokeratin-14) KRT14 Rabbit Monoclonal Antibody, Clone#RM328 (Catalog # M01432-3) . Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Keratin, type I cytoskeletal 14; Cytokeratin-14; CK-14; Keratin-14; K14; KRT14

Gene Name

KRT14

UniProt

P02533

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody reacts to human Cytokeratin-14. It may also react to mouse or rat Cytokeratin-14, as predicted by immunogen homology.

Immunogen

A peptide corresponding to C-terminus of human Cytokeratin-14

Clonality

Monoclonal

Clone

Clone: RM328

Tissue Specificity

Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.

Applications

IHC, WB

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

Molecular Weight

51561 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M01432-3

Product MSDS

https://www.bosterbio.com/msds?sku=M01432-3

Fragment

Rabbit IgG

Other Gene Names

Keratin, type I cytoskeletal 14

Subcellular Location

Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.

Prediction Reactivity

Mouse, Rat

Curated Selection

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