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Anti-Human IBA1 AIF1 Antibody

Boster Bio Anti-Human IBA1 AIF1 Antibody catalog # M01394-3. Tested in IF, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Allograft inflammatory factor 1; AIF-1; Ionized calcium-binding adapter molecule 1; Protein G1; AIF1; G1, IBA1

Gene Name

AIF1

UniProt

P55008

Host

Chicken

Reactivity

Human

Immunogen

Peptide identical to part of the C-terminal of human IBA1 coupled to KLH

Clonality

Polyclonal

Tissue Specificity

Detected in T-lymphocytes and peripheral blood mononuclear cells. .

Applications

IF, IHC, WB

Field of Research

Actin Binding Proteins, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

WB: 1:1,000-5,000. IF 1:2,000-5,000

Function

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. .

Molecular Weight

16703 MW

Shipping Conditions

Available

Storage Conditions

Store at 4&#8451

Other Gene Names

Allograft inflammatory factor 1

Subcellular Location

Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. .

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