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Anti-CK18 (Cytokeratin-18) KRT18 Rabbit Monoclonal Antibody, Clone#RM279

Boster Bio Anti-CK18 (Cytokeratin-18) KRT18 Rabbit Monoclonal Antibody, Clone#RM279 (Catalog # M01357-3) . Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18; KRT18; CYK18; PIG46

Gene Name

KRT18

UniProt

P05783

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody reacts to human CK18 (Cytokeratin-18) .

Immunogen

A peptide corresponding to the N-terminus of human Cytokeratin-18.

Clonality

Monoclonal

Clone

Clone: RM279

Tissue Specificity

Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.

Applications

IHC, WB

Field of Research

Cell Type Markers, Class I, Cytoskeleton, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Intermediate Filaments, Microtubules, Signal Transduction, Structures, Tumor Associated

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.

Molecular Weight

48058 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Keratin, type I cytoskeletal 18

Subcellular Location

Cytoplasm, perinuclear region. Nucleus, nucleolus.

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