MAO-B-IN-37
MAO-B-IN-37 (Compound 37) is a derivative of TT01001 , and a selective inhibitor for monoamine oxidase B (MAO-B) with an IC50 of 270 nM. MAO-B-IN-37 exhibits good metabolic stability in mice microsomes and good affinity with human serum albumin[1].
Product Specifications
CAS Number
894280-02-5
UNSPSC
12352211
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-37.html
Smiles
O=C(NCC1=CC=C(F)C=C1)NC2=CC=C([N+]([O-])=O)C=C2
Molecular Formula
C14H12FN3O3
Molecular Weight
289.26
References & Citations
[1]Barbosa Belchior M, et al., Synthesis and evaluation of enzyme inhibition by novel TT01001 derivatives as monoamine oxidase B inhibitors. Bioorg Med Chem Lett. 2024 Dec 2;117:130045.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B
Frequently Asked Questions
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