Anti-Arginase-1 (ARG1) Rabbit Monoclonal Antibody, Clone#RM377

Boster Bio Anti-Arginase-1 (ARG1) Rabbit Monoclonal Antibody, Clone#RM377 (Catalog # M01106-3) . Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Arginase-1;3.5.3.1 ; Liver-type arginase; Type I arginase; ARG1

Gene Name

ARG1

UniProt

P05089

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody reacts to human Arginase-1 (ARG1)

Immunogen

A peptide corresponding to the C-terminus of human Arginase-1 (ARG1)

Clonality

Monoclonal

Clone

Clone: RM377

Tissue Specificity

Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957) . Also detected in macrophages mycobacterial granulomas (PubMed:23749634) . Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409) .

Applications

IHC, WB

Field of Research

Biochemicals, Chemical Type, Neurology Process, Neuroscience

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively; the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.