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Anti-AR (N-terminal) Rabbit Monoclonal Antibody, Clone#RM254

Boster Bio Anti-AR (N-terminal) Rabbit Monoclonal Antibody, Clone#RM254 (Catalog # M00542-4) . Tested in IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR, NR3C4

Gene Name

AR

UniProt

P10275

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody reacts to full length androgen receptor and splice variants.

Immunogen

A peptide corresponding to the N-terminus of Androgen Receptor

Clonality

Monoclonal

Clone

Clone: RM254

Tissue Specificity

Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333) . Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107) .

Applications

IHC, WB

Field of Research

Cancer, Developmental Biology, Epigenetics and Nuclear Signaling, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Signaling, Nuclear Signaling Pathways, Reproduction, Signal Transduction, Signaling Pathway

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Molecular Weight

99188 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00542-4

Product MSDS

https://www.bosterbio.com/msds?sku=M00542-4

Fragment

Rabbit IgG

Other Gene Names

Androgen receptor

Subcellular Location

Nucleus. Cytoplasm. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
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