Anti-Aurora A Kinase Monoclonal Antibody
Selected Variant
M00246-4
Size: 100 µL
Boster Bio Anti-Aurora A Kinase Monoclonal Antibody catalog # M00246-4. Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Aurora kinase A-A;2.7.11.1; Aurora/IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; Serine/threonine-protein kinase 6-A; Serine/threonine-protein kinase Eg2-A; pEg2; Serine/threonine-protein kinase aurora-A; p46Eg265; aurka-a; aurka, eg2, stk6
Gene Name
Aurka-a
UniProt
Q91820
Host
Mouse
Reactivity
Human, Rat, Mouse
Immunogen
E. coli
Clonality
Monoclonal
Tissue Specificity
Highly expressed in ovary and testis. .
Applications
WB, IF, IHC
Sensitivity
>5000 cells
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Dilution
WB: 1:100-1:500. ICC/IF and IHC: 1:100-1:500.
Function
Mitotic serine/threonine kinases that contributes to the regulation of cell cycle progression. Associates with the centrosome and the spindle microtubules during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Phosphorylates numerous target proteins. Important for microtubule formation and/or stabilization. .
Molecular Weight
46372 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Aurora kinase A-A
Subcellular Location
Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes to the spindle pole during mitosis especially from prophase through anaphase. Partially colocalized with gamma tubulin in the centrosome, from S to M phase.
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