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Anti-Alpha-Synuclein SNCA Antibody

Boster Bio Anti-Alpha-Synuclein SNCA Antibody catalog # M00215-3. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Cow, Human, Mouse, Pig, Rat, Horse.

Product Specifications

Synonyms

Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP; SNCA; NACP, PARK1

Gene Name

SNCA

UniProt

P37840

Host

Chicken

Reactivity

Cow, Human, Mouse, Pig, Rat, Horse

Immunogen

Full length recombinant human protein expressed in and purified from E. coli

Clonality

Polyclonal

Tissue Specificity

Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.

Applications

IF, IHC, ICC, WB

Field of Research

Alzheimer's Disease, Neurodegenerative Disease, Neurology Process, Neuroscience

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

WB: 1:2,000 IF/ICC and IHC: 1:1,000

Function

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Molecular Weight

14460 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Alpha-synuclein

Subcellular Location

Cytoplasm, cytosol . Membrane . Nucleus . Cell junction, synapse . Secreted . Membrane-bound in dopaminergic neurons. .

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